CHATURVEDULA PRASAD V.,DUBOWCHIK GENE M.,MACOR JOHN E.
申请号:
NZ60323111
公开号:
NZ603231A
申请日:
2011.03.11
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
603231 Disclosed is the compound (R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide, or a pharmaceutically acceptable salt thereof. Also disclosed is a pharmaceutical composition comprising a therapeutically effective amount of the above compound in association with a pharmaceutically acceptable adjuvant, carrier, or diluent, for treating a condition associated with aberrant levels of CGRP or CGRP receptor signaling, and particularly for treating a condition such as migraine, neuropathic pain, breast cancer or glioma.