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Transcobalamin receptor polypeptides, nucleic acids, and modulators thereof, and related methods of use in modulating cell growth and treating cancer and cobalamin deficiency
专利权人:
发明人:
Edward V. Quadros,Jeffrey M. Sequeira
申请号:
US13967199
公开号:
US09044461B2
申请日:
2013.08.14
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides the amino acid and polynucleotide sequences of the transcobalamin receptor, as well as modulators of the transcobalamin receptor. Accordingly, the present invention provides compositions and methods for the treatment and prevention of diseases and disorders associated with cobalamin deficiency, including compositions and methods that promote cobalamin uptake. In addition, the present invention provides compositions and methods for the detection, treatment, and prevention of diseases associated with deregulated cell growth, including, e.g., cancer and autoimmune disorders, including compositions and methods that inhibit cobalamin uptake.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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