COHEN Eran;SEALANTIUM MEDICAL LTD;SCHWARTZ Yotam;LAUB Orgad
发明人:
LAUB Orgad,COHEN Eran,SCHWARTZ Yotam
申请号：
IL25878818
公开号：
IL258788D0
申请日:
2018.04.17
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
An improved fibrinogen-based tissue sealing patch having a degradation time of less than two weeks is disclosed. The patch comprises a polyethylene glycol-caprolactone-lactide (PEG-CL-LA) triblock copolymer film into which a fibrinogen-based sealant comprising less than 8 mg/cm2 fibrinogen and less than 10 IU/cm2 thrombin has been incorporated. In preferred embodiments, the polymer film comprises PEG having a molecular weight of between 3000 and 3500 and a CL:LA:PEG ratio of 34:2:1. Methods of production and use of the patch are also disclosed.
