Provided is a method for conveniently and rapidly evaluating or selecting an adiponectin secretion regulator.The method for evaluating or selecting an adiponectin secretion regulator includes the following steps (A) to (C): (A) a step of administering a test substance to an experimental animal (B) a step of inducing a sleep deprivation in the experimental animal and (C) a step of measuring blood adiponectin level of the animal, and evaluating change of the blood adiponectin level.
