您的位置: 首页 > 农业专利 > 详情页

COMPOSITIONS DE POLYPEPTIDE VARIANT DU VEGF
专利权人:
The Board of Trustees of The Leland Stanford Junior University
发明人:
COCHRAN, Jennifer R.,KAPUR, Shiven,BLUMENKRANZ, Mark S.
申请号:
EP16737999
公开号:
EP3244908A4
申请日:
2016.01.15
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Provided herein are VEGF variant polypeptides and Fc-VEGF variant polypeptide fusions, comprising a first VEGF monomer joined to a second VEGF monomer by a peptide linker or a disulfide bridge. In some embodiments, the VEGF variant polypeptides comprise the formula: A-L-B, wherein A is a first VEGF monomer subunit; B is a second VEGF monomer subunit; and L is a peptide linker having 14 to 20 amino acids. In certain embodiments, disclosed herein, are methods of treating an angiogenic disorder in an individual in need thereof, comprising administering to the individual a VEGF variant polypeptide or an Fc-VEGF variant polypeptide fusion. In certain embodiments, disclosed herein, are kits comprising a VEGF variant polypeptide or Fc-VEGF variant polypeptides.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充