It refers to the pyridine compound - [4, 5-b] - quinolin-4, 5 (3H, 10h) - formula glycol (I), wherein R1, R2, R3, R4 and R5 are defined in the descriptive report. The most popular compounds are: 2-cyclohexane-10-methyl-3-phenyl-pyridine - [4, 5-b] - quinine-4, 5 (3H, 10h) - dioxin; 10-alli-2-isopropyl-3-phenyl-pyridine - [4, 5-b] - quinine-4, 5 (3H, 10h) - dioxin, etc. He also mentioned a pharmaceutical composer These compounds are meaningless mutation inhibitors for the treatment of hemophilia A and B, cystic fibrosis.SE REFIERE A COMPUESTOS DERIVADOS DE PIRIMIDO-[4,5-b]-QUINOLIN-4,5(3H,10H)-DIONA DE FORMULA (I) DONDE R1, R2, R3, R4 Y R5 SON COMO SE DEFINEN EN LA MEMORIA DESCRIPTIVA. SON COMPUESTOS PREFERIDOS: 2-CICLOBUTIL-10-METIL-3-FENIL-PIRIMIDO-[4,5-b]-QUINOLINA-4,5(3H,10H)-DIONA; 10-ALIL-2-ISOPROPIL-3-FENIL-PIRIMIDO-[4,5-b]-QUINOLINA-4,5(3H,10H)-DIONA; ENTRE OTROS. TAMBIEN SE REFIERE A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON SUPRESORES DE MUTACIONES SIN SENTIDO SIENDO UTILES EN EL TRATAMIENTO DE HEMOFILIA A Y B, FIBROSIS QUISTICA