THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY
发明人:
SEDEGAH, MARTHA,RICHIE, THOMAS
申请号:
EP10830313
公开号:
EP2451477A4
申请日:
2010.11.09
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention relates immunogenic polypeptides and epitopes from Plasmodium falciparum protein AMA1. The epitopes contain HLA class I binding motifs and stimulate an anti-malaria CD8+ T-cell response. The polypeptides can be incorporated into immunogenic formulations against malaria. Additionally, the antigens are useful for facilitating evaluation of immunogenicity of candidate malaria vaccines.