PLASMODIUM FALCIPARUM HLA CLASS I RESTRICTED T-CELL EPITOPES

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专利权人:

发明人:

申请号：

EP10830313.2

公开号：

EP2451477A1

申请日:

2010.11.09

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The invention relates immunogenic polypeptides and epitopes from Plasmodium falciparum protein AMA1. The epitopes contain HLA class I binding motifs and stimulate an anti-malaria CD8+ T-cell response. The polypeptides can be incorporated into immunogenic formulations against malaria. Additionally, the antigens are useful for facilitating evaluation of immunogenicity of candidate malaria vaccines.

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