The present invention relates to pharmaceutical compositions for treating thermal injuries and wounds combined with bone injuries. More specifically, the present invention relates to a pharmaceutical composition for treating thermal injuries and wounds combined with bone injuries characterized in consisting of the following components: 4-12% beeswax , and 88-96% sesame oil extract containing the raw material of thes drugs Scutellaria baicalensis, Coptis chinensis, golden cypress, pericarpium papaveris and earthworms of the total weight of the pharmaceutical composition, wherein the raw materials of the drugs Scutellaria baicalensis, Coptis chinensis, golden cypress, pericarpium papaveris and earthworms are respectively present in 1-6% of the total dry weight of the sesame oil by weight. The pharmaceutical composition of the present invention can treat thermal injuries involving human skin, subcutaneous tissues and bones, as well as involving bone wounds, especially open fractures, deep thermal injuries combined with bone injuries, and deep thermal injuries combined with bone necrosis caused by trauma, such as deep burns combined with bone injuries or bone necrosis.