DAVIS GEORGE,데이비스 조지,LO WILLIAM,로 윌리엄,RENGA JAMES,렌가 제임스,TISDELL FRANCIS,티스델 프랜시스,YAP MAURICE,얍 모리스,YOUNG DAVID,영 데이빗
申请号：
KR1020117027465
公开号：
KR1020120016247A
申请日:
2010.05.03
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
Various aspects disclosed herein relate to aryl substituted aminopyrimidines according to Formula 1: wherein, X1 is N or C&mdash；R3； X2 is N or C&mdash；R4 provided that X1 and X2 are not both N； R1-R7 are H, CN, CHO, &mdash；SCN, NO2, F, Cl, Br, I, substituted or unsubstituted C1-C4-alkyl, substituted or unsubstituted halo-C1-C4-alkyl, substituted or unsubstituted C1-C4-alkoxy, substituted or unsubstituted halo-C1-C4-alkoxy, substituted or unsubstituted C1-C4-thioalkyl, substituted or unsubstituted halo-C1-C4-thioalkyl, substituted or unsubstituted C3-C-7-cycloalkyl, substituted or unsubstituted C2-C4-alkenyl, C2-C4-alkynyl, substituted or unsubstituted C1-C4-acylalkyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-amino, C1-C4-alkyl-S(O)&boxH；NH, substituted or unsubstituted aryl, substituted or unsubstituted heterocycle, wherein the substituents are one or more of the following F, Cl, Br, OH, CN, NO2, CHO, &mdash；SCN, S(O)n-C1-C4-alkyl (where n=0-2), C1-C4-alkyl, halo-C1-C4-alkyl, C1-C4-alkylamine, C1-C4-alkoxy, halo-C1-C4-alkoxy, C1-C4-thioalkyl, halo-C1-C4-thioalkyl, C1-C4-alkylacyl, C1-C4-acyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxy-imino, hydroxy-imino； C1-C4-alkyl-S(O)&boxH；NH； and Q is a substituted or unsubstituted aryl, substituted or unsubstituted heterocycle wherein the substituents of Q are taken from R1-R7.본원에 개시된 다양한 양태는 화학식 I에 따른 아릴 치환된 아미노피리미딘에 관한 것이다.<；화학식 I>；여기서, X1은 N 또는 C-R3이고； X2는 N 또는 C-R4이되 X1과 X2가 모두 N은 아니고； R1 내지 R7은 H, CN, CHO, -SCN, NO2, F, Cl, Br, I, 치환 또는 비치환 C1-C4-알킬, 치환 또는 비치환 할로-C1-C4-알킬, 치환 또는 비치환 C1-C4-알콕시, 치환 또는 비치환 할로-C1-C4-알콕시, 치환 또는 비치환 C1-C4-티오알킬, 치환 또는 비치환 할로-C1-C4-티오알킬, 치환 또는 비치환 C3-C7-시클로알킬, 치환 또는 비치환 C2-C4-알케닐, C2-C4-알키닐, 치환 또는 비치환 C1-C4-아실알킬, C1-C4-아실옥시, C1-C4 알콕시카르보닐, C1-C4-알콕시-아미노, C1-C4-알킬-S(O)=NH, 치환 또는 비치환 아릴, 치환 또는 비치환 복소환이고, 여기서 치환기는 F, Cl, Br, OH, CN, NO2, CHO, -SCN, S(O)n-C1-C4-알킬(여기서 n은 0 내지 2임), C1-C4-알킬, 할로-C1-C4-알킬, C1-C4-알킬아민, C1-C4-알콕시, 할로-C1-C4-알콕시, C1-C4-티오알킬, 할로-C1-C4-티오알킬, C1-C4-알킬아실, C1-C4-
