Grant C. Churchill,Sridhar R. Vasudevan,Nisha Singh
申请号：
US13983011
公开号：
US20140094449A1
申请日:
2012.01.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to sulphur- and/or selenium-containing compounds that can inhibit the enzyme inositol mono-phosphatase (IMPase), and which can be used in treating conditions that are treatable through inhibition of this enzyme, such as bi-polar disorder, the compounds having a structure of Formula (I), or is a pharmaceutically acceptable salt thereof Formula (I) in which: E is S or Se and each of phenyl rings A and B is optionally substituted with one or more substituents, in which each substituent is selected independently from: (1) a halogen, which is preferably selected from F, Cl and Br (2) C1-C4 alkyl, such as C1-C2 alkyl or C1 alkyl, optionally substituted with one or more halogen atoms, each of which is preferably selected from F, Cl and Br and (3) C1-C4 alkoxy, such as C1-C2 alkoxy or C1 alkoxy optionally substituted with one or more halogen atoms, each of which is preferably selected from F, Cl and Br.
