METHODS AND POLYPEPTIDES FOR MODULATION OF IMMUNORESPONSE

• 收藏
• 分享

专利权人:

发明人:

LU YEN TA,CHANG CHIA MING,WEI TSAI YIN

申请号：

IN201827000199

公开号：

IN201827000199A

申请日:

2018.01.02

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The disclosure found that TLT 1 directly binds to immune cells and triggers cells to express immunosuppressive phenotypes； i.e. down regulation of HLA DR and up regulation of PD L1. The induction of PD L1 and reduction of HLA DR by TLT 1 or TLT 1 derived polypeptides can therefore be useful in treating diseases associated with immune hyper reactivity such as autoimmune diseases hypersensitivity reactions transplantation rejections and graft versus host disorders.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/