METHOD FOR THE EXTRACTION OF FURAN DERIVATIVE COMPOUNDS FROM SEEDS OF HASS AVOCADO (Persea americana Mill) AT LOW TEMPERATURE AND THEIR USE AS REPELLENTS AND MITICIDES AGAINST Tetranychus urticae, Tetranychus cinnabarinus, Oligonychus yothersi, Panonychus citri, and Brevipalpus chilensis.
This invention relates to the extraction and use of bioactive compounds from avocado seeds (var. Hass; Persea americana Mill) at room temperature. The extraction was performed with dichloromethane as a solvent using a simple diffusion mechanism within pressed avocado seeds. The extracted compounds were identified as furan derivative structures and fragments derived thereof that exhibited repellent and miticide activity against mite species of economic interest: Tetranychus urticae, Tetranychus cinnabarinus, Oligonychus yothersi, Panonychus citri, and Brevipalpus chilensis. The compounds obtained have the general structure of a disubstituted furan, as illustrated in FIG. 1, and the fragments thereof are derived from mono-substituted furans and from side-chain fragments. The utility of these compounds as repellents was determined over a 48-hour period, and their function as miticides was evaluated for 24 hours after application.
