Process for preparating (6R)-L-erythrotetrahydrobiopterin hydrochloride crystalline form B from other crystalline forms

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专利权人:

Merck & Cie

发明人:

申请号：

EP04820966.2

公开号：

EP1687308B1

申请日:

2004.17.11

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Crystal forms of (6R)-L-erythro-tetrahydrobiopterin dihydrochloride, hydrates and solvates and processes for their preparation are provided. These crystal forms are either intermedi­ates for the preparation of stable polymorphic form B or are suitable for solid formulations.

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