HUANG, CHENG PO,黄政博,黃政博,CHEN, TENG HAI,陈登海,陳登海,CHEN, KUANG DEE,陈光地,陳光地,SU, CHUN TAO,苏钧陶,蘇鈞陶
申请号：
TW103119831
公开号：
TWI527828B
申请日:
2014.06.09
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
Disclosed herein is a novel triterpenoid and its use in the treatment or prophylaxis of a kidney disease. The novel triterpenoid is capable of reducing the levels of blood urine nitrogen (BUN) and serum creatinine, which are factors associated with inflammation of kidney as well as increasing the level of glomerular filtration rate (GFR). Therefore, the novel triterpenoid is useful for the manufacture of a medicament for the treatment and/or prophylaxis of a kidney disease, including acute kidney injury and chronic kidney inflammation.本文揭示一種新穎的三萜化合物及其用來治療或預防腎臟病的藥學用途。所揭示的新穎三萜化合物可以降低與腎臟發炎相關之生化指標物(如,血清中尿素氮(BUN)或肌酐酸(CRE))含量以及提高腎小球過濾率(GFR),因此可用來製造能治療或預防腎臟病的藥物。
