PROBLEM TO BE SOLVED: To provide a method for producing an optically active compound that is very useful for the synthesis of NITD609 having antimalarial activity, and a production method for NITD609.SOLUTION: The present invention provides a method for producing an optically active compound represented by general formula (1), useful as an intermediate in NITD609 production, the optically active compound produced by the reaction between a compound represented by general formula (2) and a compound represented by general formula (3), in the presence of a copper complex catalyst comprising an asymmetric ligand represented by formula (A) (R, Rand Rare H or a protecting group of an amino group； Rand Rare a substituted/unsubstituted aromatic group).SELECTED DRAWING: None【課題】抗マラリア活性を有するＮＩＴＤ６０９の合成に非常に有用な光学活性化合物を製造する方法、並びにＮＩＴＤ６０９の製造方法の提供。【解決手段】ＮＩＴＤ６０９の製造の中間体として有用な一般式（１）で表される光学活性化合物の製造方法であって、一般式（２）で表される化合物と一般式（３）で表される化合物とを、式（Ａ）で表される不斉配位子を含有する銅錯体触媒の存在下で反応させる製造方法。（Ｒ１、Ｒ２及びＲ１３はＨ又はアミノ基の保護基；Ｒ１１及びＲ１２は置換／非置換の芳香族基）【選択図】なし
