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Triazinone compound and T-type calcium channel inhibitor
专利权人:
日産化学工業株式会社
发明人:
齊藤 憲子,江木 淳,長井 宏,上野 恵,新谷 友輔,稲葉 祐介,安達 倫明,平井 祐一,川津 猛,安武 晃一,高橋 大樹
申请号:
JP2014508105
公开号:
JP6304492B2
申请日:
2013.03.29
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: where each substituent is defined in detail in the description or claims, for example R 1 is H or C 1-6 alkoxy, etc., each of L 1 and L 2 is independently a single bond or NR 2 , etc., L 3 is C 1-6 alkylene, etc., A is C 6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc., B is C 3-11 cycloalkylene, etc., D is C 6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc.
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