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TRIAZINONE COMPOUND AND T-TYPE CALCIUM CHANNEL INHIBITOR
专利权人:
NISSAN CHEMICAL INDUSTRIES; LTD.
发明人:
SAITO, NORIKO,EGI, JUN,NAGAI, HIROSHI,UENO, MEGUMI,SHINTANI, YUSUKE,INABA, YUSUKE,ADACHI, MICHIAKI,HIRAI, YUICHI,KAWAZU, TAKESHI,YASUTAKE, KOICHI,TAKAHASHI, DAIKI
申请号:
EP13769812
公开号:
EP2832728A4
申请日:
2013.03.29
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: where each substituent is defined in detail in the description or claims, for example R 1 is H or C 1-6 alkoxy, etc., each of L 1 and L 2 is independently a single bond or NR 2 , etc., L 3 is C 1-6 alkylene, etc., A is C 6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc., B is C 3-11 cycloalkylene, etc., D is C 6-14 aryl or 5 to 10-membered heteroaryl which is optionally substituted, etc.
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