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CYCLIC AMIDES AS POTASSIUM CHANNEL OPENERS
专利权人:
Acousia Therapeutics GmbH
发明人:
BÖS, Michael
申请号:
DK18707374
公开号:
DK3484863T3
申请日:
2018.02.27
申请国别(地区):
DK
年份:
2020
代理人:
摘要:
The present invention discloses novel compounds which are useful as potassium channel openers, in particular as openers of the Kv7.4 potassium channel. The novel compounds are compounds according to formula I, wherein - n = 0 or 1 , - RL is a substituent selected from the group consisting of unsubstituted or substituted cycloalkyl groups, alkylcycloalkyl groups, aryl groups, arylalkyl groups and arylcycloalkyl groups, which optionally contain heteroatoms, and - RR is a substituent selected from the group consisting of unsubstituted or substituted aryl groups, alkylaryl groups, and arylalkyl groups, which optionally contain heteroatoms, - or a stereoisomer, a tautomer, a prodrug or a salt, preferably pharmaceutically acceptable salt thereof.
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