您的位置: 首页 > 农业专利 > 详情页

METHOD FOR PRODUCING DISINTEGRATING PARTICULATE COMPOSITION COMPRISING ACID-TYPE CARBOXYMETHYLCELLULOSE, DISINTEGRATING PARTICULATE COMPOSITION COMPRISING ACID-TYPE CARBOXYMETHYLCELLULOSE, AND ORALLY DISINTEGRATING TABLET INCLUDING DISINTEGRATING PARTICULATE COMPOSITION COMPRISING ACID-TYPE CARBOXYMETHYLCELLULOSE
专利权人:
NICHIRIN CHEMICAL INDUSTRIES, LTD.;DAICEL CORPORATION
发明人:
Takahiro HIRAMURA,Kiyoshi lkura,Sae ltaya,Tomohito Okabayashi,Naohiro Hashikawa,Tetsuro Morita,Kimiko Ikeda,Haruka Wakayama
申请号:
US16600066
公开号:
US20200038332A1
申请日:
2019.10.11
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present application provides an orally-disintegrating tablet having excellent tablet hardness and disintegrability. The present application further provides a method of producing a disintegrative particulate composition including three components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component and an excipient. The method includes a first wet granulation step using any two of the three components, and a second wet granulation step using granules obtained in the first wet granulation step and the remaining one component of the three components not used in the first wet granulation step. The production method may further includes a crystalline cellulose as a fourth component or a third step of mixing a crystalline cellulose into granules obtained in the second wet granulation step. Disintegrative particulate compositions obtained by these methods are also disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充