COMPOSITION DE PARTICULE SE DÉSINTÉGRANT CONTENANT DE LA CARBOXYMÉTHYLCELLULOSE DE TYPE ACIDE ET DE LA CELLULOSE CRISTALLINE, ET COMPRIMÉ SE DÉSINTÉGRANT ORALEMENT CONTENANT LADITE COMPOSITION
HIRAMURA TAKAHIRO,IKURA KIYOSHI,ISHIKAWA SAE,OKABAYASHI TOMOHITO,HASHIKAWA NAOHIRO,MORITA TETSURO,IKEDA KIMIKO
申请号:
EP13840080
公开号:
EP2898899A4
申请日:
2013.09.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
An object of the present application is to provide an orally-disintegrating tablet having excellent tablet hardness and disintegrability, and including a disintegrative particulate composition. This invention relates to a disintegrative particulate composition comprising the four components consisting of a first disintegrator component of an acid-type carboxymethylcellulose, a second disintegrator component other than the acid-type carboxymethylcellulose, an excipient of a sugar or sugar alcohol, and crystalline cellulose; and to an orally-disintegrating tablet, including the disintegrative particulate composition and a medicinal ingredient.