NEW AMINOPYRROLO[1,2-A]INDOLE AND AMINOPYRIDAZINO[1,6-A]INDOLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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专利权人:

发明人:

BRION, JEAN-DANIEL,GALTIER, CHRISTOPHE,HERVET, MAUD,LE STRAT, FRÉDÉRIC,MOREAU, ANNE,RENKO, ZAFIARISOA DOLOR,LE RIDANT, ALAIN,HARPEY, CATHERINE

申请号：

MYPI 20092661

公开号：

MY145623A

申请日:

2008.01.04

申请国别(地区):

MY

年份:

2012

代理人:

摘要：

COMPOUNDS OF FORMULA (1)WHEREIN: -X REPRESENTS CO OR R1, R4 REPRESENT HYDROGEN, (C1-C6)ALKYL, (C1-C6)AMINOALKYL, (C1-C6)HYDROXYALKYL, ARYL(C1-C6)ALKYL, R2, R3 REPRESENT HYDROGEN, (C1-C6)ALKYL, (C1-C6)AMINOALKYL, (C1-C6)HYDROXYALKYL, OR (R1 AND R2), (R3 AND R4), TOGETHER WITH THE CARBON ATOMS CARRYING THEM, FARM A CARBON- CARBON BOND, R5, R6 REPRESENT HYDROGEN, (C1-C6)ALKYL, R7, R8, REPRESENT HYDROGEN, (C1-C6)ALKYL, ARYL-(C1-C6)ALKYL, (C2-C6)ALKENYL, (C2-C6)- ALKYNYL, A SUBSTITUTED (C1-C6)ALKYL CHAIN, CYANO, (C1-C6)ALKOXY, NR13R14, A SUBSTITUTED (C1-C6)ALKENYL CHAIN OR A SUBSTITUTED (C1-C6)ALKYNYL CHAIN, (R5 AND R8), (R6 AND R7), TOGETHER WITH THE CARBON AND NITROGEN ATOMS CARRYING THEM, FORM AN OPTIONALLY SUBSTITUTED HETEROCYCLE HAVING 5, 6 OR 7 RING MEMBERS, R9 REPRESENTS HYDROGEN, HALOGEN, (C1-C6)ALKYL, (C1-C6)ALKOXY, HYDROXY, CYANO, NITRO, (C1-C6)POLYHALOALKYL, NRI5R16, OR A SUBSTITUTED (C1-C6)ALKYL CHAIN, N REPRESENTS AN INTEGER 0, 1, 2, 3 OR 4, R10 REPRESENTS HYDROGEN, (C1-C6)ALKYL, (C2-C6)ALKENYL, ARYL-(C1-C6)ALKYL, (C1-C6)- POLYHALOALKYL, OR A SUBSTITUTED (C1-C6)ALKYL CHAIN, R11, RI2, REPRESENT -COOT OR –CH2O-U, R13, RI4, REPRESENT HYDROGEN OR (C1-C6)ALKYL OR, TOGETHER WITH THE NITROGEN ATOM CARRYING THEM, FORM A HETEROCYCLE HAVING FROM 4 TO 8 RING MEMBERS, RI5, RI6, REPRESENT HYDROGEN OR (C1-C6)ALKYL, (C2-C6)ALKENYL, THEIR ENANTIOMERS, DIASTEREOISOMERS, N-OXIDES, AND ALSO ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID OR BASE, MEDICAMENTS.

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