Compound of formula (I) have antibacterial activity: wherein: m is 0 or 1； Q is hydrogen or cyclopropyl； AIk is an optionally substituted, divalent C1-C6 alkylene, alkenylene or alkynylene radical which may contain an ether (&mdash；O&mdash；), thioether (&mdash；S&mdash；) or amino (&mdash；NR)&mdash； link, wherein R is hydrogen, &mdash；CN or C1-C3 alkyl； X is &mdash；C(&boxH；O)NR6&mdash；, or &mdash；C(&boxH；O)O&mdash； wherein R6 is hydrogen, optionally substituted C1-C6 alkyl, C2-C6 alkenyl or C2-C6 alkynyl； Z1 is &mdash；N&boxH； or &mdash；CH&boxH；Z2 is &mdash；N&boxH； or &mdash；C(R1)&boxH；； R1 is hydrogen, methyl, ethyl, ethenyl, ethynyl, methoxy, mercapto, mercaptomethyl, halo, fully or partially fluorinated (C1-C2)alkyl, (C1-C2JaIkoxy or (C1-C2)alkylthio, nitro, or nitrile (&mdash；CN)； R2 is a group Q1-[Alk1]q-Q2-, wherein q is 0 or 1； AIk1 is an optionally substituted, divalent, straight chain or branched C1-C6 alkylene, or C2-C6 alkenylene or C2-C6 alkynylene radical which may contain or terminate in an ether (&mdash；O&mdash；), thioether (&mdash；S&mdash；) or amino (&mdash；NR)&mdash； link； Q2 is an optionally substituted divalent monocyclic carbocyclic or heterocyclic radical having 5 or 6 ring atoms or an optionally substituted divalent bicyclic carbocyclic or heterocyclic radical having 9 or 10 ring atoms； Q1 is hydrogen, an optional substituent, or an optionally substituted carbocyclic or heterocyclic radical having 3-7 ring atoms.
