PRODUCTION OF THIOESTERS USING SORTASE

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专利权人:

发明人:

Martin Schatte,Mara Boenitz-Dulat,Frank Bergmann

申请号：

US15933741

公开号：

US20180334661A1

申请日:

2018.03.23

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Herein is reported a method for the enzymatic production of a thioester comprising incubating i) a first polypeptide comprising the amino acid sequence LPXTG (SEQ ID NO: 01, wherein X can be any amino acid residue), ii) a second polypeptide that has at its N-terminus a cysteine amino acid residue or is a cysteinyl compound, and iii) a third polypeptide with sortase A activity.

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