The present invention relates to a pharmaceutical composition for improving, preventing or treating inflammatory-mediated inflammatory diseases. More particularly, the present invention relates to a pharmaceutical composition for preventing or treating inflammation-mediated inflammatory diseases, which comprises a culture medium containing Pseudomonas sp . recruitment domain) to inhibit polymer formation, thereby promoting inhibition of inflammation activity, thereby exerting an effect on improvement, prevention or treatment of the above diseases.인플라마좀 매개 염증성 질환의 개선, 예방 또는 치료용 약학 조성물에 관한 것으로, 슈도모나스(Pseudomonas) 속 균주 배양액을 포함하는 조성물을 사용하는 경우 체내 ASC(adaptor protein apoptosis-associated spec-like protein containing a caspase-recruitment domain) 중합체 형성을 억제하여 인플라마좀 활성 억제를 촉진시켜 상기 질환의 개선, 예방 또는 치료에 효과를 발휘할 수 있다.
