Compositions comprising indometacine, its pharmaceutically acceptable salts and cocrystals； and process for the preparation

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专利权人:

DARHOLDING KFT.

发明人:

FILIPCSEI GENOVEVA,OETVOES ZSOLT,HELTOVICS GABOR,DARVAS FERENC

申请号：

HU1400104

公开号：

HU1400104A2

申请日:

2014.02.25

申请国别(地区):

HU

年份:

2015

代理人:

摘要：

The invention relates to a nanostructured (nanoparticular) composition comprising Indomethacine, its pharmaceutically acceptable salts and co-crystals, processes for the preparation thereof, and compositions useful for pharmaceutical applications. The size of the nanoparticles according to the invention is smaller than 500 nm. Indomethacine (INN) or Indomethacine (USAN, previously BAN) is a non-steroidal anti-inflammatory drug (NSAID), which is used for the treatment of fever, inflammation, spasm, swells and inflammations. The machanism of action of Indomethacine is the inhibition of the synthesis of prostaglandin. It is marketed under the trade names of Indocin, Indocid, Indochron E-R, and Indocin-SR.

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