SUMMARY OF THE INVENTION [Pachyrhizus erosusThe present invention relates to a pharmaceutical composition and a health functional food for the prevention or treatment / improvement of thrombotic disorders containing an underground part of the extract of Yambin as an active ingredient. More specifically, The present invention relates to a pharmaceutical composition and a health functional food for preventing or treating / improving a thrombotic disease which contains a fraction obtained as a sequential solvent fraction of the above extract as an active ingredient. The pharmaceutical composition for the prevention or treatment / improvement of the thrombotic disease of the present invention and the extract of yambin as an active ingredient of the health functional food can be obtained by extracting the yambi root mass under hot water or ethanol, And fractions obtained by successively fractionating the extract with hexane, ethyl acetate and butanol. The above-mentioned active ingredient is prepared by using an enzyme (thrombin and prothrombin) associated with thrombus formation and a strong And exhibits antithrombotic activity and has an excellent effect that can be used for prevention and treatment of thrombotic diseases such as ischemic stroke and hemorrhagic stroke through improvement of blood circulation due to inhibition of platelet aggregation. In particular, the yamvin extract and the active fraction of the present invention are excellent in thermal stability and exhibit no inhibition of blood coagulation factor inhibition, thrombogenesis-related enzyme inhibition and platelet aggregation inhibition effect even in an acidic condition of pH 2 and in plasma, It is an extremely useful invention in the pharmaceutical industry and the food industry because it has excellent hemolytic activity and can be prepared into various forms such as extract, powder, ring, and tablet, so that it can be prepared at any time.본 발명은 얌빈(Pachyrhizus erosus)의 지하부 추출물을 유효성분으로 함유하는 혈전성 질환
