Chatelier, Ronald C.,Hodges, Alastair McIndoe,Verity, Bruce
申请号：
ES10180699
公开号：
ES2661543T3
申请日:
2007.03.30
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A method of reducing the effect of interfering in an assay for analyte concentration, comprising: (a) introducing a sample having an analyte into an electrochemical cell to initiate a reaction with a reagent in the cells, the electrochemical cells comprising the first and second electrodes in a separation ratio, and a first reagent each, the first reagent layer comprising an enzyme and a mediator (b) applying to the cell a first test potential having a first polarity, measuring a first transient of current, and to determine a first current value of the peak of the first current transient (c) apply to the cell a second test potential that has a second polarity, where the first polarity is opposite to the second polarity, measure a second current transient, determine a second peak current value from the second current transient and determine a first current value based on an integral of current values during a time interval of the second current transient； (d) calculate a corrected current value based on the first peak current value and the second peak current value by eliminating an interference current value of the first current value, the corrected current value being proportional to the analyte concentration within of the sample； (e) calculate the analyte concentration based on the corrected current value.Un método para reducir el efecto de interferente en un ensayo para la concentración de analito, que comprende: (a) introducir una muestra que tiene un analito en una célula electroquímica para iniciar una reacción con un reactivo en la células, la células electroquímica comprendiendo el primer y segundo electrodos en una relación de separación, y una primera cada de reactivo, la primera capa de reactivo comprendiendo una enzima y un mediador (b) aplicar a la célula un primer potencial de ensayo que tiene una primera polaridad, medir un primer transitorio de corriente, y determinar un primer valor de corriente del pico del primer transitorio de corriente (c) aplic
