CONJUGUÉS DE DISORAZOLES ET LEURS DÉRIVÉS AVEC DES MOLÉCULES SE FIXANT À DES CELLULES, NOUVEAUX DÉRIVÉS DE DISORAZOLE ET PROCÉDÉS DE FABRICATION ET D'UTILISATION DE CES CONJUGUÉS ET DÉRIVÉS

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专利权人:

ÆTERNA ZENTARIS GMBH

发明人:

申请号：

EP07803270.3

公开号：

EP2066679B1

申请日:

2007.09.06

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention provides conjugates of disorazoles and their derivatives with cell-binding molecules, such as peptides, proteins, hormones, blood proteins and antibodies. The present invention further provides novel disorazole derivatives and processes of manufacturing such conjugates and disorazole derivatives. These compounds can be used as medicaments for the treatment of physiological and/or pathophysiological conditions in mammals, in particular for the treatment of various tumors.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/