Substituted arylsulphonylglycines, the preparation thereof and the use thereof as pharmaceutical compositions

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专利权人:

Holger Wagner

发明人:

Holger Wagner,Elke Langkopf,Matthias Eckhardt,Ruediger Streicher,Corinna Schoelch,Annette Schuler-Metz,Alexander Pautsch

申请号：

US12530507

公开号：

US08232312B2

申请日:

2008.03.14

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to substituted arylsulphonylglycines of general formula (I) wherein R, X, Y and Z are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen-associated protein phosphatase 1 (PP1), and their use as pharmaceutical compositions.

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