LRK2 is inhibited by substituted pyrazolpyridan derivatives, its preparation procedure, pharmacological synthesis, pharmacological combination, and the use of the compound to prevent or treat selected cancer and neurodegenerative diseases.
MCIVER EDWARD GILES,SMILJANIC ELA,HARDING DENISE JAMILLA,HOUGH JOANNE.
申请号:
CL2011002267
公开号:
CL2011002267A1
申请日:
2011.09.13
申请国别(地区):
CL
年份:
2012
代理人:
摘要:
Compound derived from pirazolopiridina replacedLRRK2 kinase inhibitor; procedure of preparation of said Compound Pharmaceutical composition, pharmaceutical use of compound; Combination; to prevent or treat a disorder selected dAnd Cancer and Neurodegenerative Diseases.Compuesto derivado de pirazolopiridina sustituida, inhibidor de la cinasa lrrk2; procedimiento de preparación de dicho compuesto; composición farmacéutica; combinación farmacéutica; uso del compuesto para prevenir o tratar un trastorno seleccionado de cáncer y enfermedades neurodegenerativas.