Francisco GONZALEZ-BOBES,David Alan CONLON,Paul C. LOBBEN,Justin Lockheart BURT,Joshua ENGSTROM,Carolyn S. WEI,Jason J. ZHU,Yu FAN
申请号:
US14774522
公开号:
US20160022675A1
申请日:
2014.03.12
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and compositions comprising the tetrahydroisoquinolines and other compounds, e.g, intermediates and by-products of the processes described herein. Pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression are also disclosed.