PAUL LOBBEN,RULIN ZHAO,BEI WANG,BANG CHI CHEN,SHUANG LIU,MIN HU,YUH LIN ALLEN YANG,MATTHEW ISHERWOOD,RASIDUL AMIN,WENGE CUI
申请号:
IN8606/DELNP/2010
公开号:
IN2010DN08606A
申请日:
2010.12.03
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-l,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form.