Consejo Nacional De Investigaciones Cientificas Y Tecnicas;Asociación Civil De Estudios Superiores;Inis Biotech LLC
发明人:
申请号:
EP14842369.2
公开号:
EP3047275A4
申请日:
2014.09.05
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present application is directed to compositions and methods for treating a subject with cancer and/or increasing migration of a mesenchymal stromal cells (MSCs) stimulated with a recombinant autocrine motility factor (rAMF) to a tumor or a tumor cell, e.g. hepatocellular carcinoma (HCC). In addition, methods for increasing adhesion of MSCs to endothelial cells with rAMF are disclosed. In some embodiments, the MSCs comprise a therapeutic agent, e.g., an anti-tumor agent.