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CELLULES SOUCHES MESENCHYMATEUSES POUR AMELIORER L'ACTIVITE ANTITUMORALE D'UNE IMMUNOTHERAPIE
专利权人:
APCETH GMBH & CO. KG
发明人:
HERMANN, FELIX,GUENTHER, CHRISTINE,GEUMANN, ULF
申请号:
CA3008352
公开号:
CA3008352A1
申请日:
2017.03.31
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to mesenchymal stem cells (MSCs) for use in the treatment of a tumor, wherein said treatment comprises the combined administration of said mesenchymal stem cells with an anti-tumor immunotherapy, and wherein said MSCs do not comprise exogenous nucleic acids that encode immune response-stimulating cytokines. In a preferred embodiment the invention relates to the use of said MSCs in the treatment of a tumor and/or malignant disease, wherein the anti-tumor immunotherapy for combined administration comprises the administration of a cellular immunotherapy, preferably chimeric antigen receptor (CAR) T cells, wherein said T cell receptor binds specifically to a tumor-associated antigen, and the mesenchymal stem cells are not genetically modified.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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