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MEDICINAL FORMS OF IRON (III) CITRATE
专利权人:
КЕРИКС БАЙОФАРМАСЬЮТИКАЛЗ; ИНК. (US)
发明人:
ЛИ Генри Тронг (US)
申请号:
RU2014123503/15
公开号:
RU2014123503A
申请日:
2014.06.09
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A tablet containing granular particles, wherein said granular particles contain iron (III) citrate and a binder, wherein the ratio of the average area to the mass of said granular particles is 1 mn gram or more. 2. A tablet according to claim 1, wherein the ratio of the average area to the mass of said granular particles is 5 mn grams or more. A tablet according to claim 1, wherein the ratio of the average area to the mass of said granular particles is 10 mn grams or more. A tablet according to claim 1, which contains at least 70 wt.% Iron (III) citrate. 5. A tablet according to claim 1, which contains at least 80 wt.% Iron (III) citrate. 6. A tablet according to claim 1, which contains at least 90 wt.% Iron (III) citrate. 7. A tablet according to claim 1, wherein the binder consists of one or more of hydroxypropyl cellulose (HPC), hydroxypropyl methyl cellulose (HPMC), sodium alginate, alginic acid, guar gum, gum arabic, xanthan gum, carbopol, gum cellulose (carboxymethyl cellulose, ethyl) maltodextrin, PVP / VA, povidone, microcrystalline cellulose, starch (partially or fully pregelatinized starch) and methyl cellulose. 8. The tablet according to claim 1, in which the% of water determined by measuring the loss during drying (LOD) is less than 20 wt./wt. %.nine. The tablet according to claim 1, in which the% of water, determined by measuring loss during drying (LOD), is less than 15 wt./wt. %.10. The tablet according to claim 1, in which the% of water determined by measuring the loss during drying (LOD) is less than 10 wt./wt. %.eleven. The tablet according to claim 1, which further comprises a baking powder1. Таблетка, содержащая гранулированные частицы, где указанные гранулированные частицы содержат цитрат железа (III) и связующее, при этом отношение средней площади к массе указанных гранулированных частиц равно 1 мна грамм или превышает это значение.2. Таблетка по п. 1, в которой отношение средней площади к массе указанных гранулированных частиц равно 5 мна г
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