Ahmed Z. El-Hashim;Ivan O. Edafiogho;Samuel B. Kombian;Mariam H. Yousif
发明人:
Ahmed Z. El-Hashim,Ivan O. Edafiogho,Samuel B. Kombian,Mariam H. Yousif
申请号：
US12662364
公开号：
US09238019B2
申请日:
2010.04.13
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The antitussive and bronchodilator use for an enaminone ester relates to the use of ethyl 4-[(4-chlorophenyl)amino]-6-methyl-2-oxocyclohex-3-en-1-oate (also referred to as “enaminone E121”) for treatment of respiratory conditions, and particularly to use of the ester as the active ingredient in a cough suppressant for nonproductive cough. The ester may be used to achieve an antitussive effect, a bronchodilator effect, or both in a patient in need thereof. The ester may be formulated in any desired delivery form (such as a tablet, a capsule, a time-release capsule, a syrup, a liquid, an injection, a spray, or an inhalant), and be combined with any suitable pharmaceutical carrier, vehicles, binders, fillers, disintegrators, lubricants, solubilizers, emulsifiers, surfactants, and other excipients.
