INDUCTEURS DE PETITES MOLECULES DE DERIVES REACTIFS DE L'OXYGENE ET INHIBITEURS DE L'ACTIVITE MITOCHONDRIALE

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专利权人:

UNIVERSITA DEGLI STUDI DI SASSARI;THE REGENTS OF THE UNIVERSITY OF MICHIGAN

发明人:

NEAMATI, NOURI,SECHI, MARIO

申请号：

CA3017142

公开号：

CA3017142A1

申请日:

2017.03.07

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/