УНИВЕРСИТА ДЕЛЬИ СТУДИ ДИ САССАРИ (IT);ДЗЕ РИДЖЕНТС ОФ ДЗЕ ЮНИВЕРСИТИ ОФ МИЧИГАН (US)
发明人:
НЕАМАТИ, Нури (US),СЕКИ, Марио (IT)
申请号：
RU2018135141
公开号：
RU2018135141A
申请日:
2017.03.07
申请国别(地区):
RU
年份:
2020
代理人:
摘要：
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.
