PROBLEM TO BE SOLVED: To provide a skin care preparation suitable as a cosmetic (including quasi medicine), etc.SOLUTION: The skin care preparation comprises an acyl derivative of serine and a compound represented by the general formula [wherein R4 is an unsubstituted or substituent-containing aromatic group or hydrogen atom R5 and R6 are each independently an unsubstituted or substituent-containing aromatic group X is a nitrogen atom or oxygen atom R7 and R8 are each present in the number depending on X and are each independently 1-6C alkyl in which a hydrogen atom or carbon atom may be substituted with a heteroatom or hydrogen atom].COPYRIGHT: (C)2013,JPO&INPIT【課題】化粧料(但し、医薬部外品を含む)等に好適な、皮膚外用剤の提供。【解決手段】セリンのアシル誘導体及び下記一般式に表される化合物を含有する皮膚外用剤。[式中、R4は、無置換又は置換基を有する芳香族基、水素原子を表し、R5及びR6は、それぞれ独立に、無置換又は置換基を有する芳香族基を表し、Xは、窒素原子又は酸素原子を表し、R7及びR8は、Xに応じた数で存在し、それぞれ独立に、水素原子又は炭素原子が複素原子に置換されていても良い炭素数1~6のアルキル基、水素原子を表す。]【選択図】なし
