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Utilities of amide compounds
专利权人:
Teruo Yamamori
发明人:
Teruo Yamamori,Kiyoshi Nagata,Natsuki Ishizuka,Katsunori Sakai
申请号:
US12081662
公开号:
US08106051B2
申请日:
2008.04.18
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds having an activity to enhance the expression of apoAI are provided, which are used as medicaments.Compounds of formula (I):in which ring A and Ar1 are independently a monocyclic or bicyclic aromatic carbocyclic group or aromatic heterocyclic group, each of which may be optionally substituted, or the like R is a hydrogen or the like Z is oxygen or the like Y1 and Y2 are a hydrogen, a lower alkyl, or the like n is an integer of 0 to 2 the broken line is the presence or absence of a bond and the wavy line represents a cis- or trans-geometrical isomerism with respect to the double bond are disclosed.
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