The invention concerns a process for making compounds using wastes of natural origin and fibres of plant or animal origin, wherein wastes of natural origin, fibres of plant origin, as well as wastes of animal origin, composing the so-called "charge", are mixed with agglomerating plastic materials, the so-called "carriers", and with agglomerating additives in order to form a mixture, the so-called "blend", which is transformed into a compound, the "compound", used for making semi-finished products. Said process occurs five sequenced steps that goes from the preparation of the "charge" and the "blend" to the selection of the "carriers" and agglomerating additives till the process of the "blend" to obtain the "compound" and finally to the process of the "compound" to obtain a semi-finished product. According to the invention the initial "charge" is submitted to a sanitization treatment, based on the principle of advanced oxidation, obtained by applying the technological process referred to as "Non-thermal plasma" or "NTP", where the so- called "non-thermal discharges with dielectric-barrier method" or "DBDs" are used, in order to strongly reduce bacterial charges, until removal thereof, decompose the volatile organic substances (VOCs) and remove smells.L'invention concerne un procédé de fabrication de composés utilisant des déchets d'origine naturelle et des fibres d'origine végétale ou animale, des déchets d'origine naturelle, des fibres d'origine végétale, ainsi que des déchets d'origine animale, composant ce que l'on appelle la "charge", sont mélangés avec des matières plastiques agglomérantes, ce que l'on appelle les "supports", et avec des additifs agglomérants pour former une mixture, ce que l'on appelle le "mélange", qui est transformé en un composé, le "composé", utilisé pour la fabrication de produits semi-finis. Ledit procédé se déroule en cinq étapes séquencées qui vont de la préparation de la "charge" et du "mélange" à la sélection des "supports" et des add