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TWO OR MORE VOLATILE SOLVENT-CONTAINING COMPOSITIONS AND METHODS FOR DERMAL DELIVERY OF DRUGS
专利权人:
Kevin S. Warner;Jie Zhang;Sanjay Sharma
发明人:
Jie Zhang,Kevin S. Warner,Sanjay Sharma
申请号:
US13566273
公开号:
US20120294926A1
申请日:
2012.08.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is drawn to adhesive formulations and methods of drug delivery. The formulation can include a drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least two volatile solvents, and a non-volatile solvent system including at least one non-volatile solvent, wherein at least one non-volatile solvent is capable of facilitating the delivery of the drug at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
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