Eric C. Scribben,Steven M. Risser,Amy M. Heintz,Jeffrey L. Ellis,John D. Clay,Timothy M. Blum
申请号：
US14356859
公开号：
US20140324022A1
申请日:
2012.11.07
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.
