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Crystallization process of aripiprazole derivatives in extended release formulations for treatment of schizophrenia
专利权人:
Alkermes Pharma Ireland Limited
发明人:
Morales, Wilfredo Jr.,Zeidan, Tarek A.,Charella, Renato A.,Wright, Steven G.,Perry, Jason M.
申请号:
AU2015306910
公开号:
AU2015306910A1
申请日:
2015.08.24
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
Processes for providing depot injections of recrystallized aripiprazole lauroxil in which particles of the aripiprazole lauroxil have a surface area of about 0.50 to about 3.3 m 2/g; and crystals of aripiprazole lauroxil produced by such processes. The present invention provides a process for making a compound of Formula (A) in crystal form wherein Ra is CH20C(O)R and wherein R1 is a substituted or unsubstituted aliphatic moiety.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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