Stephen John Freese,Annaliesa Anderson,Viliam Pavliak,Kathrin Ute Jansen,Ingrid Lea Scully,Tracy Dee Scott,Jasdeep Singh Nanra,A. Krishna Prasad,Bruce Arthur Green
申请号：
US14811017
公开号：
US20160022798A1
申请日:
2015.07.28
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to immunogenic conjugates comprising S. auerus serotype 5 and 8 capsular polysaccharides conjugated to carrier proteins and methods for their preparation and use. Methods for making the immunogenic conjugates of the invention involve covalent conjugation of the capsular polysaccharides with the carrier proteins using conjugation chemistry involving either 1,1-carboyl-di-1,2,4-triazole (CDT) or 3-(2-pyridyldithio)-propionyl hydrazide (PDPH).
