This invention generally pertains to the field of psychiatry. In particular,this invention pertains to the discovery that agents which inhibit the bindingof cortisol to its receptors can be used in methods for treating delirium.Mifepristone, a potent specific glucocorticoid receptor antagonist, can beused in these methods. The invention also provides a kit for treating deliriumin a human including a glucocorticoid receptor antagonist and instructionalmaterial teaching the indications, dosage and schedule of administration ofthe glucocorticoid receptor antagonist.