Reelin degradation using ADAMTS-3

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专利权人:

公立大学法人名古屋市立大学

发明人:

服部 光治,河野 孝夫,久永 有紗,鯉江 真利,鈴木 健太

申请号：

JP2012180354

公开号：

JP5838481B2

申请日:

2012.08.16

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

[Problem] To identify an enzyme that decomposes active reelin into an inactive form and to provide an effective treatment and research means for diseases such as Alzheimer's disease based on active reelin decrease using this enzyme and/or a gene thereof. [Solution] ADAMTS-3, which is used to decompose active reelin into inactive reelin, and functional derivatives thereof. A method for using ADAMTS-3 that uses ADAMTS-3 or a functional derivative thereof for treatment or research relating to the physiologic functions of reelin or the promotion or suppression thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/