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PHARMACEUTICAL COMPOSITION FOR MODIFIED DELIVERY OF ACTIVES
专利权人:
发明人:
申请号:
EP10816429.4
公开号:
EP2521537A2
申请日:
2010.12.30
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
There is provided a modified release pharmaceutical dosage form for the delivery of the therapeutically active pharmaceutical ingredient wherein the dosage form comprises a swellable core comprising therapeutically active pharmaceutical ingredient and one or more swellable hydrophilic polymers, one or more rate controlling polymeric coating(s) surrounding the core wherein the core upon contact with gastrointestinal fluids swells and exerts a pressure which causes partial disruption of the rate controlling coating surrounding the core and modified release is achieved by the combination of swellability and rate controlling ability of polymer in core and area of disruption of rate controlling polymer surrounding the core.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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