COMPOSITION PHARMACEUTIQUE LIQUIDE

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专利权人:

ARES TRADING S.A.

发明人:

FREITAG, ANGELIKA,HAWE, ANDREA,RINALDI, GIANLUCA,DEL RIO, ALESSANDRA

申请号：

CA2970577

公开号：

CA2970577A1

申请日:

2015.12.17

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention relates to novel liquid protein formulations, particularly arginine-free liquid pharmaceutical compositions of etanercept. The invention employs particular combinations and classes of buffer systems, tonicifiers, and sugar stabilisers, optionally alongside polar ionisable amino acids (e.g. aspartic acid, glutamic acid, histidine, and lysine), to afford a viable and storable drug product.

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